UFR : Faculté de pharmacie, Université Paris-Saclay
Nom : ONGERI
Prénom : Sandrine
Equipe de recherche
- Intitulé : BioCIS
- Numéro : UMR CNRS Univ. Paris Sud 8076
- Thématiques : Chimie du Fluor, chimie médicinale, peptidomimétiques, inhibiteurs d’agrégation de protéines amyloïdes, inhibiteurs du protéasome, biophysique, physicochimie.
Principales publications
- R. Fanelli, A. S. Ressurreiçao, L. Dufau, J.-L. Soulier, A. Vidu, N. Tonali, G. Bernadat, M. Reboud-Ravaux, S. Ongeri. "Introduction of polar groups on the naphthalene scaffold of molecular tongs inhibiting wild-type and mutated HIV-1 protease dimerization" MedChemComm 2014, 5, 719 - 727.
- M. Keita, J. Kaffy, C. Troufflard, E. Morvan, B. Crousse and S. Ongeri. "19F NMR Monitoring of the Eukaryotic 20S Proteasome Chymotrypsin-like Activity: Investigative tool for studying Allosteric Regulation" Org. Biomol. Chem. 2014, 12, 4576 – 4581.
- J. Kaffy, D. Brinet, J-L Soulier, L. Khemtémourian, O. Lequin, M. Taverna, B. Crousse, S. Ongeri. "Structure-activity Relationships of Sugar-based peptidomimetics as modulators of amyloid β-peptide early oligomerization and fibrillization"; Eur. J. Med. Chem. 2014, 86, 752-758.
- L. Vahdati, R. Fanelli, G. Bernadat, I. Correia, O. Lequin, S. Ongeri, U. Piarulli. "Synthesis and Conformational Studies of a Stable Peptidomimetic β-Hairpin Based on a Bifunctional Diketopiperazine Turn Inducer" , New J. Chem. 2015, 39, 3250-3258.
- J. Kaffy, D. Brinet, J-L Soulier, I. Correia, N. Tonali, K. F. Fera, Y. Iacone, A. R. F. Hoffmann, L. Khemtémourian, B. Crousse, M. Taylor, D. Allsop, M. Taverna, O. Lequin, S. Ongeri. "Designed Glycopeptidomimetics Disrupt Protein−Protein Interactions Mediating Amyloid β Peptide Aggregation and Restore Neuroblastoma Cell Viability", J. Med. Chem. 2016, 59, 2025−2040.
