UFR Pharmacie de Reims

URCA (Université de Reims Champagne Ardenne)

Intitulé : ICMR (Institut de Chimie Moléculaire de Reims), axe « Conception d’Inhibiteurs Enzymatiques »
Numéro : UMR CNRS 7312
Thématiques : Pharmaco-chimie, développement méthodologique, Chemodiversité

Mots clés : Chimie hétérocyclique, pharmaco-chimie, inhibiteur enzymatique

M. Pudlo, I. Allart-Simon, B. Tinant, S. Gérard* and J. Sapi, "First domino radical cyclisation / Smiles rearrangement combination", Chemical Communication 2012, 48, 2442-2444.
A. Sukhorukov, Y. Boyko, Y. Nelyubina, S. Gerard, S. Ioffe, V. Tartakovsky, L. Malleret, and A. Belaaouaj, "Synthesis of PDE IVb Inhibitors. 3. Synthesis of (+)-, (−)-, and (±)-7-[3-(cyclopentyloxy)-4-methoxyphenyl]hexahydro-3H-pyrrolizin-3-one via reductive domino transformations of 3-β-carbomethoxyethyl-substituted six-membered cyclic nitronates" J. Org. Chem. 2012, 77, 5465−5469
C. Szalata, J. Szymoniak, F. Fabis, S. Butt-Gueule, S. Rault, P. Bertus,* S. Gérard* and J. Sapi, "Cyclopropanated tryptamine analogues: Synthesis and biological evaluation as 5-HT6 receptor-ligands". Chemistry and Medicinal Chemistry 2013, 8, 70-73.
M. Gurry, I. Allart-Simon, P. McArdle, S. Gérard, J. Sapi and F. Aldabbagh, "Photochemical aryl radical cyclizations to give (E)-3-Y|ideneoxindoles" , Molecules 2014, 19, 15891-15899.
A. Renzetti, A. Marrone, S. Gérard, J. Sapi, H. Nakazawa, N. Re and A. Fontana, "TiCl₄-promoted condensation of methyl acetoacetate, isobutyraldehyde, and indole: a theoretical and experimental study" , Phys. Chem. Chem. Phys. 2015, 17, 8964-8972.